The 3CPM® Company’s Electrogastrogram (EGG) Machine is an analysis system that records, stores, displays and prints the myoelectric signals from the stomach as an aid to diagnosis of various gastric motility disorders.  In particular, it allows the doctor to divide disorders of stomach motility into different subtypes based upon the EGG signal.  Once the subtypes of disease are known, it is then possible to treat or even cure disorders like gastroparesis in a more personalized manner, ensuring successful treatment.

An EGG is a non-invasive test of gastric myoelectrical activity of the stomach. The EGG reflects the stomach’s pacesetter potential activities, much like the electrocardiogram (ECG) reflects electrical events occurring in the heart. The performance of an EGG does not require pre-medication and has no significant side effects.

An Electrogastrogram is indicated for patients who have:

  • Gastroparesis

  • Unexplained nausea, bloating, early satiety

  • Unexplained dyspepsia

  • Chronic GERD

In its position paper on nausea and vomiting, the American Gastroenterological Association included Electrogastrogram in its algorithm for the evaluation and management of nausea. Optimum use of this device requires a basic familiarity with the published literature which describes typical EGG patterns commonly encountered in clinical practice with specific patient groups and related interpretative techniques.

The secret of the technology is the Human Interface Module or HID. Inside of the device are special filters that have characteristic amplifiers to allow detection of biological signals with approximate frequency ranges from 1 to 15 cycles per minute (cpm) to pass through for recording and digitization.  Two channels of data are recorded during the session.

One channel supplies the Electrogastrogram signal; the other channel records respiratory rates.  This respiratory recording channel is used to help identify artifact in the EGG signal caused by movement, deep breathing, etc.

The analog signals recorded from the EGG skin electrodes and the respiratory belt are amplified, filtered and fed into four cables.  The cables are connected to a computer which has been equipped with a special analog to digital (A/D) converter for digitization of the Electrogastrogram signal. The data file that is created during the A/D conversion of the EGG signal undergoes Fourier transform (FFT), an analysis of the frequencies contained in the EGG signal and a running spectral analysis (RSA).  A plot of the RSA and calculation of the percentage of power in selected frequency bands are reports produced by the Electrogastrogram analysis system.

In its position paper on nausea and vomiting, the American Gastroenterological Association included Electrogastrogram in its algorithm for the evaluation and management of nausea. Optimum use of this device requires a basic familiarity with the published literature which describes typical EGG patterns commonly encountered in clinical practice with specific patient groups and related interpretative techniques.

The secret of the technology is the Human Interface Module or HID. Inside of the device are special filters that have characteristic amplifiers to allow detection of biological signals with approximate frequency ranges from 1 to 15 cycles per minute (cpm) to pass through for recording and digitization. 

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The Electrogastrogram data is presented in four major frequency ranges

  • Normal (2.5 to 3.75 cpm)

  • Bradygastria (1.0-2.5 cpm)

  • Tachygastria (3.75-10.0 cpm)

  • Duodenal-Respiratory (10.0-15 cpm)

YOU MAY HAVE A CURABLE FORM OF GASTROPARESIS

Of the estimated 40 million Americans that suffer from this disease, 25-28% have a subtype that can be cured with simple endoscopic balloon dilation.

Gastroparesis

Gastroparesis may be divided into subtypes that include obstructive, reflux related, and poor conduction types. Only the EGG can properly identify the type of dysmotility and lead to either correction or proper treatment and control. In obstructive subtypes, 3CPM® Company EGG GMAT® software successfully predicts a 93% response to endoscopic pyloric balloon dilation.

GERD – reflux disease

Up to 40-45% of people who suffer from GERD have gastroparesis and symptoms of bloating and satiety. Associated EGG definable subtypes include functional obstruction and reflux related or GERD+. Reflux related subtypes are cured with correction of the GERD, while obstructive subtypes require pyloric therapy. Obstructive subtypes require resolution prior to correction of reflux to avoid potential complications. 

Nausea, Vomiting and Dyspepsia

These symptoms are often due to poor conduction associated to low numbers of ICCs. The quality of the 3CPM signal correlates directly with quality and numbers of the ICC’s. Normal ICC quality correlates directly with the success of therapy like medication or the Enterra stimulator for gastroparesis. If poor ICC’s are noted, then therapy is directed towards restoration of the ICC’s.

One of the most important features about the 3CPM technology is that the signal of the individual person is able to be compared to population based normal parameters to determine if the signal is normal or abnormal.

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